HORDB

General Information

ID: hor001123
Uniprot ID: NA
Protein name: GYIRFamide
Gene name: NA
Organism: Schistosoma mansoni
Family: FMRFamide related peptide family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: NA
GO MF: NA
GO BP: NA
GO CC: NA

Sequence Information

Sequence: GYIRF
Length: 5
Propeptide: NA
Signal peptide: NA
Modification: T5 Phenylalanine amide
Glycosylation: NA
Mutagenesis: NA

Activity

Function: In males they provide innervation to the dorso-ventral muscle fibres of the gynaecophoric canal, and in females they innervate the circular and longitudinal muscle fibres of the ootype.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure

Disulfide bond: NA
Structure ID: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001123_AF2.pdb

hor001123_ESM.pdb

Physical Information

Mass:	72629	Formula:	C32H46N8O7
Absent amino acids:	ACDEHKLMNPQSTVW	Common amino acids:	FGIRY
pI:	9.35	Basic residues:	1
Polar residues:	2	Hydrophobic residues:	2
Hydrophobicity:	22	Boman Index:	-622
Half-Life:	30 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	78
Instability Index:	-898	Extinction Coefficient cystines:	1490
Absorbance 280nm:	372.5

Literature

PubMed ID: 11085236
Title: A Confocal Microscopical Study of the Musculature of Adult Schistosoma Mansoni